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Description

A high-fiber diet in high IS producers shifts tryptophan metabolism to reduce levels of IS

doi: 10.3390/ijms23042215 267

A 2019 study in the British Journal of Clinical Pharmacology found that a single 800 mg EGCG dose decreased midazolam (a CYP3A4 probe) AUC by approximately 18% in healthy volunteers, suggesting meaningful CYP3A4 modulation [9]