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10.1016/j.biopha.2019.109635 42 JavaheriB.PouletB.AljazzarA.de SouzaR.PilesM.HopkinsonM.et al (2017)

Further research is undoubtedly needed to fully elucidate the role of peripheral tissues in PD, with subsequent translation of these findings into clinical practice

They found that early intervention in the form of strict control of blood glucose, lipids, and blood pressure, along with correction of dietary habits to control fat intake and long-term physical exercise can improve several indicators of kidney prognosis, including macroalbuminuria, GFR decline rate, ESRD and death [84]