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Above pH 10.6, all functional groups are deprotonated, and the negative charge is maximal, binding to trivalent cations

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The occurrence of ferroptosis also has a regulatory impact on autophagy

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Likewise, given during reperfusion after clamping the common carotid arteries, BPC 157 reduced stroke (i.e., both early and delayed hippocampal neural damage, achieving full functional recovery in the Morris water maze test, inclined beam-walking test, and lateral push test) (Vukojevic et al., 2020) or reduced L-NAME-induced retinal ischemia in rats (Zlatar et al., 2021)