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The PRKN -linked, autosomal-recessive variant of PD (ARPD) is characterized by the selective degeneration of dopamine and noradrenaline producing neurons in the S

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Despite the lack of definite pathogen-associated molecule pattern (PAMP) of SARS-CoV-2, in analogy with SARS-CoV and MERS-CoV, it can be speculated that upon cellular entry of SARS-CoV-2 via its ACE2 receptor, viral genomic single-stranded RNA or other RNA compositions (double-stranded RNA) as PAMPs can be sensed by the related PRRs, including TLRs and RLRs in host cells