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Table 2 The present NNMT inhibitors

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Moreover, differences in strain selection, dosage, administration timing, and patients baseline microecological status among different clinical trials are important factors leading to inconsistent results

GHR binding induces receptor dimerisation and activation of the associated Janus kinase 2 (JAK2), triggering a phosphorylation cascade that activates Signal Transducer and Activator of Transcription 5 (STAT5) the primary transcriptional mediator of GHs genomic effects, including IGF-1 gene expression

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