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To improve our detection resolution, we also performed gradients where we added a final concentration of 1.3 M TAMRA-FP Serine-Hydrolase probe (TAMRA) (ThermoFisher) to the starting 1 M LPL mixture

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Phase 2 trial data published in the New England Journal of Medicine (2023) demonstrated average reductions in body weight exceeding 20% over 48 weeks in some participants

doi: 10.1111/jdi.12965 47