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Heterogeneity was negligible ( I 2 =0%)

Reference data from the Pediatric Advanced Life Support guidelines were used as the benchmark

Previous in vivo human data have shown that the plasma concentrations of APR-246 in the 12 h following its intravenous administration range from 50 to 500 mM, suggesting that concentrations above 50 mM are suitable for in vitro studies of the early effects of APR-246

however, these expressions were not significant when compared to the control

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The composites were subjected to high-temperature treatment and etching to produce nanosized CDs