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K-means clustering was performed on the genera relative abundance data using the R script in the Supplementary Materials Scripts .zip file (KMScript), and clusters were plotted

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GHK-Cu improves overall skin appearance, stimulates wound healing, protects skin cells from UV radiation, reduces inflammation and free radical damage, and increases hair growth and thickness, enlarging hair follicle size

The three proline residues at positions 35 (the PPP motif) rigidify the chain and hinder access by proteolytic enzymes a molecular explanation of the peptide stability in the gastrointestinal environment described in the literature