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Sustained use of Diane 35 over 3-4 months leads to considerable reductions in acne severity, number of lesions, and acne-related quality of life indicators

This is likely achieved by promoting epithelial cell renewal and activating inflammation-induced signal transducer and activator of transcription 3 (STAT3) in IECs, which results in the expression of downstream targets (e.g., Reg3 ) essential for cell proliferation and tissue regeneration [35]

This mechanism may be associated with pyroptosis-induced mitochondrial ROS release and disruption of membrane integrity

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Chan, Z., K

In this study, the content of CAT, ascorbate peroxidase, guaiacol peroxidase, and SOD increased with increasing the concentration of CeO 2 NPs, which indicates the antioxidant defense system in apples