glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of Glutathione-responsive prodrug conjugates for image-guided

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of Glutathione-responsive prodrug conjugates for image-guided
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SKU: 85438404997
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Glutathione responsive prodrug conjugates for image guided combination in cancer therapy ScienceDirect Synthesis of glutathione responsive, amphiphilic methotrexate based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer ScienceDirect PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis Redox Responsive Polyprodrugs: Recent Innovations in Reduction and Oxidation Responsive Drug Delivery Systems Chemistry of Materials Dual pH redox responsive hyperbranched polymeric nanocarriers with TME trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer Scientific Reports Emerging Strategies in Stimuli Responsive Prodrug Nanosystems for Cancer Therapy ACS Nano

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10.3892/ijmm.2015.2412 67 LiuM.LiuS.ZhangQ.FangY.YuY.ZhuL.et al (2021)

80 LiuJ.KuangF.KroemerG.KlionskyD

Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm

Emerging CAR-macrophage (CAR-M) platforms, exemplified by anti-HER2 CAR-Ms, not only mediate the direct phagocytosis of tumor cells but also potentiate antigen presentation and pro-inflammatory cytokine release (187)