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Although there was no significant difference by age in the abundance of these double-positive cells across all time points, there was a significant difference at day 3.5 between the young and old ages (Students t -test, * P value = 0.03) and the young and geriatric ages (Students t -test, * P value = 0.01

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Outcome measures All patients were followed up at the outpatient clinic or via telephone at predetermined intervals

doi:10.1179/1476830513Y.0000000073 121

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The diaries offered eight possibilities to be checked by the patients each hour of the day between sleep, dyskinesia (severe, moderate, mild), off period (severe, moderate, mild) and on without dyskinesia period (Supplementary Home Diary)