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Cell 187(5):1177-1190.e18 Zhang F et al (2023) Current insights into the functional roles of ferroptosis in musculoskeletal diseases and therapeutic implications

However, age-related changes in neutrophil function have significant implications for the immune response (Fig

Increasing plasma GSH concentrations by oral administration has been shown to increase the availability of GSH for transport into these tissues

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This can result in immune dysregulation and reduced self-tolerance

Randomized phase II study of pembrolizumab after stereotactic body radiotherapy (SBRT) versus pembrolizumab alone in patients with advanced non-small cell lung cancer: the PEMBRO-RT study