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[DOI] [PubMed] [Google Scholar] 116.Biehs B et al

When the storage capacity is exceeded, accumulated cholesterol crystallizes, leading to hepatocyte apoptosis and the release of cholesterol-crystal-laden lipid droplets ( Figure 2D ) ( In contrast, SAMs accumulate in fibrotic regions and exhibit a pro-fibrogenic transcriptomic profile ( Figure 2E )

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Transport and disposition of uric acid in the brain The concentrations of UA are, as mentioned, substantially lower in the CSF than in peripheral blood, indicating that UA does not rapidly equilibrate across the BBB and that there may be active transport mechanisms influencing CNS UA

Liang S, Liu Y, Zhu H, Liao G, Zhu W, Zhang L, editors

2004;98:c15c24