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The ability to hybridize will depend on both the degree of complementarity and the length of the antisense nucleic acid

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If the parent compound is very hydrophilic (NAC), TPP + modification will likely induce a greater fold difference in antiproliferative effect and inhibition of mitochondrial respiration in tumor cells 36 due to the more negative mitochondrial membrane potential of tumor cells as compared with normal cells 20,21,37,38,39

Characterizing trajectories of cognitive functioning in older adults with schizophrenia: does method matter