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These modifications grant it pharmacokinetic properties absent in peptides oral bioavailability, protease resistance, and efficient blood-brain barrier penetration but also mean its metabolic fate and tissue distribution may differ substantially from peptide-class compounds

However, the adverse events were described as mainly transient and mild-to-moderate in severity

The important distinctions are labeled dosing versus compounded-unit math, escalation and missed-dose rules, measurement errors, tolerability, and the symptoms that should trigger a call to a licensed prescriber