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MeCbl was unable to inhibit the GSDME-NT-induced LDH release, further supporting that MeCbl engages GSDME but not its activated form GSDME-NT

Martinou JC, Youle RJ (2011) Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics

Figure 3 4.1.1 Role of iron metabolism in ischemic stroke Prior to the formal identification of ferroptosis, studies had already linked iron accumulation to neuronal damage in both clinical settings and animal models of cerebral ischemia (131)

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The reaction was continued at 25C overnight

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