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In DKD, upregulation of local angiotensin II in the renal tubule, activation of vascular endothelial growth factor (VEGF), and reduction of nitric oxide (NO) (60) can lead to constriction of both the afferent and efferent arterioles, as well as the interlobular arteries, compromising blood flow regulation

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doi: 10.1007/s11356021-130836 38 WHO

Treatment of the degenerated intervertebral disc

4.5 TrxR1 from human serum samples exists in high-molecular-weight forms with potential activity To gain more information about the status of extracellular TrxR1 in a biological system, we obtained human serum samples, which were the remaining parts of the previous experiments