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Here we show that part of therapeutic effect of artificial tears supplemented with L-carnitine likely stems from its inhibition of TRPV1-induced keratocyte transdifferentiation into myofibroblasts

While defects in carnitine biosynthesis do not result in carnitine deficiency, severe plasma and intracellular carnitine depletion occurs due to defects in carnitine transport [5]

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2.3.1 PBMC In brief, the stored PBMC pellets were thawed, buffered with Tris base, and lysed by sonication (15 min, 30C)

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