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doi: 10.1097/00003677-200307000-00009

Despite 5-fluorouracil (5-FU) being a primary treatment for CRC, resistance to 5-FU often leads to treatment failure and relapses

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Furthermore, the construction of a regulatory network in the high cuproptosis-OXPHOS group identified high-mobility group A1 (HMGA1) as a critical transcription factor that modulates cuproptosis, offering new insights into targeted therapeutic strategies [62]

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In the cases of deep pigmentation in the pores, Q-switched lasers are used to attack the melanin, and carbon peels deep-clean the follicles of strawberry legs and hands