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Nature 388(6642):539547 Hunt R, Xiao S, Megraud F, Leon-Barau R, Bazzoli F, Van der Merwe S, Le Mair A (2011) World Gastroenterology Organization Global Guideline

Vascular obstruction by lipid-rich plaques This 68-year-old man presents with bilateral exertional lower extremity pain relieved by rest, absent pedal pulses, and atrophic skin changes in the setting of multiple cardiovascular risk factors

Based on this background, the present study aimed to identify plasma metabolomic signatures associated with ASD by comparing children with ASD and neurotypical controls