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In most cases, Leigh disease is inherited as an autosomal recessive trait

During KD implementation, tumor cells have limited access to glucose and cannot use KBs as an energy source owing to aberrant mitochondrial function and reduced enzymatic activity for ketone consumption, which makes the KD a promising approach for cancer prevention

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A 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) highlighted that patients with post-viral dysautonomia and ME/CFS often exhibit markedly abnormal levels of plasma carnitine and free fatty acids

Nuclear Receptors Nomenclature Committee

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