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Oxygen status of lung granulomas in Mycobacterium tuberculosis -infected mice

Glutathione system The glutathione (GSH) system is a major thiol-based defense system against oxidative and electrophilic stress in mammals and functions as co-substrate for the GPxs, which efficiently remove H 2 O 2 thereby preventing oxidative insults and influencing together with glutaredoxin (Grx) the redox state of proteins via reversible S-glutathionylation [97]

Hence, the process of membrane remodeling is fundamentally different, and the requirements for the lipid cofactor might also be different

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Rodrigues, M., Ezzedine, K., Hamzavi, I., Pandya, A

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