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Biol Psychiatry 45:417421 Mishima K, Okawa M, Hozumi S, Hishikawa Y (2000) Supplementary administration of artificial bright light and melatonin as potent treatment for disorganized circadian rest-activity and dysfunctional autonomic and neuroendocrine systems in institutionalized demented elderly persons

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Advances in Experimental Medicine and Biology, 681, 107-116

B12 injections deliver vitamin B12 directly into the bloodstream, bypassing the digestive system for fast absorption

This partnership makes the combination more effective than taking either nutrient alone

The cut-off value between low, intermediate, and high-risk groups were 55 and 154, respectively