glutathione persister cells

glutathione persister cells Drug-tolerant cancer are vulnerable to GPX4 inhibition Plasticity, signaling, and metabolic rewiring

Name: glutathione persister cells Drug-tolerant cancer are vulnerable to GPX4 inhibition Plasticity, signaling, and metabolic rewiring
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Plasticity, signaling, and metabolic rewiring in melanoma persister cells Communications Biology Selective Small Molecule Activator of Patient Derived GPX4 Variant ACS Chemical Biology Glutathione Peroxidases: An Emerging and Promising Therapeutic Target for Pancreatic Cancer Treatment Additional data demonstrating that persister cells have a disabled Download Scientific Diagram Role of Glutathione in Cancer: From Mechanisms to Therapies Targeting of vulnerabilities of drug tolerant persisters identified through functional genetics delays tumor relapse: Cell Reports Medicine

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Materials and Methods Animals and Surgery

HGF mimetic activity was typically assessed by one or both of two methods: augmentation of HGF-dependent c-Met phosphorylation in HEK293 cells, or 2) augmentation of HGF-dependent cell scattering in MDCK cells

Cell Transfection Cells were transfected with the plasmid encoding CD36 (Sino Biological, Beijing, China) using the Lipofectamine 3000 reagent (Thermo Fisher Scientific, Waltham, Massachusetts, USA) for 48 h