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A 12-week trial in 71 women with photoaging showed measurable increases in skin density and thickness, reduced laxity, and improved fine line and wrinkle depth with GHK-Cu

Notably, most clinical investigations studied women (1404 female versus 83 male participants), which is expected since estrogen declines after age 30 years, and further estrogen decline with aging represents health challenges, as well as a reduction in QOL [9, 10, 19,20,21,22] and a degradation in the most visible organ of the bodythe skin [9, 10]

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Mitochondria, as the major site of oxidative reactions, must maintain sufficient levels of GSH to perform protective and biosynthetic functions 2

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Muir CS, Nectoux J, Staszewski J