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A total of 189 samples of BP were examined for pesticide adulteration in China, which showed the detection of insecticides such as chlorpyrifos, fenpropathrin, thiamethoxam, imidacloprid, and bifenthrin and fungicides such as triadimefon and carbendazim while acaricides such as fluvalinate and coumaphos were also found in BP samples (85)

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Therefore, a better understanding of the mitochondrial metabolic programmes critical in supporting cancer cell survival following 5FU treatment is required to rationally design more effective fluoropyrimidine-based chemotherapy combination regimens