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2.2 Studies on the mechanism of autophagy regulated by the mTOR-mediated nutrient sensing pathway in DKD Nutrient sensing pathways, including those involving AMPK, mTOR, and Sirt1, have been widely recognized for their roles in regulating autophagy in diabetic complications (Figure 1

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doi: 10.3389/fimmu.2021.686240 237 GhezziLCantoniCPingetGVZhouYPiccioL

Role for glutathione peroxidase-4 in brain development and neuronal apoptosis: Specific induction of enzyme expression in reactive astrocytes following brain injury