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doi: 10.3389/fmolb.2025.1608853, [DOI] [PMC free article] [PubMed] [Google Scholar]

ZnT10, though classically assigned to Golgi and endosomal compartments, can also traffic to the plasma membrane under specific conditions, such as high extracellular zinc or altered manganese levels, possessing a dynamic role in metal detoxification 32

doi:10.4103/jpp.JPP_173_16

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For example, RMCs are found throughout the entire retina and can therefore be a useful carrier for somatic gene therapy, providing nutrients to the retina and preventing or even reversing damage of optic nerve

Specifically, natural compounds provide a unique starting point, offering structural diversity, multitarget activity, and inherent biocompatibility that are highly relevant for treating ocular TB (Maiolini et al., 2020)