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NG2 glia generate new oligodendrocytes but few astrocytes in a murine experimental autoimmune encephalomyelitis model of demyelinating disease

857067.10.3389/fphar.2022.857067 Hu J et al (2022) Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway Br J Pharmacol, 179(15): p

Collectively, this raises the notion that the observed differences here are perhaps related to long-term selenium intake, a micronutrient that has been speculated to play a role in konzo pathogenesis, due to its essential requirement for maintaining antioxidant machinery 18

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Several approaches have been explored, including targeting inflammasome activation, inhibiting caspase-1, employing anti-inflammatory agents, and modulating the gut microbiota and bile acid metabolism