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INTRODUCTION Type 1 diabetes (T1D) is a chronic autoimmune condition marked by the destruction of insulin-producing cells in the pancreas, resulting in insulin deficiency

80,97,98,99,100,101 A detailed history taking identifies symptoms related to sensory, motor, and autonomic dysfunction, while a physical examination focuses on sensory and motor deficits, and reflex abnormalities

Consequently, accurately assessing the risk of neutropenia, promptly identifying febrile neutropenia and infections, and implementing appropriate preventive and therapeutic measures are crucial for mitigating anticancer therapy-related complications, enhancing the safety and effectiveness of anticancer therapy

Combination therapy with metformin, pioglitazone and vitamin B12 supplementation may provide the most prominent protective effect against DNP (7,49,72,96)

It works by stimulating lipolysis without affecting insulin sensitivity or cell growth, making it a focused tool for fat reduction

If the ligament tears away from the bone, it may take a small chip of the bone with it