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Dimerization, disulphide bond formation and metal ion acquisition are the canonical SOD1 PTM steps en route to forming a stable and active enzyme 5,6,7

[DOI] [PubMed] [Google Scholar] 172.Martens E.C., Chiang H.C., Gordon J.I

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10.1111/trf.12855

From a methodological point of view, these two models were fundamentally different, which hinted to the robustness of the results, highlighting the hypothesis that pathologic involvement in PD was not only of brain dopaminergic systems but also of non-dopaminergic systems in the brain as well as peripheral and autonomic systems

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