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phosphorylated (activated) JNK can phosphorylate Jun, a member of the AP1 transcriptional regulator, thus eliciting a JNK-dependent apoptotic cascade [11], [12]

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De Falco L, Sanchez M, Silvestri L, Kannengiesser C, Muckenthaler MU, Iolascon A, Gouya L, Camaschella C, Beaumont C

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