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In the UK, B12 replacement is typically administered via intramuscular hydroxocobalamin injections for patients with confirmed deficiency, particularly those with malabsorption or pernicious anaemia, as specified in the BNF and NICE CKS guidance on B12 and folate deficiency anaemia

or 8 p.m

10 mg Flexeril 1 tablet 2 times daily

However, people with low energy or less mobility may benefit more from larger MIC b12 doses

The treatment was 1,000 g of cyanocobalamin (n=54), 1,000 g of cyanocobalamin plus 400 g of folate (n=51), and a placebo (n=57)