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-KG: -keto-glutarate

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We found that pharmacological MT1 and MT2 agonism failed to replicate the effects of melatonin in suppressing IL-5 production ( Figures 3B, D ) or IL-13 production ( Figures 3C, E )

As it is an important glycerol and water transporter involved in cutaneous water retention, CBD may improve skin water content also by increasing AQP3 expression in skin keratinocytes (Ikarashi et al

However, despite these early observations about the metabolism of innate immune cells, it is only more recently that we have begun to elucidate the mechanisms behind these metabolic changes, and appreciate their impact on immune function