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Mechanism of Action Research Ipamorelin acts as an agonist at the growth hormone secretagogue receptor (GHSR-1a), the same receptor targeted by the endogenous peptide ghrelin

Sermorelin is injected with a insulin needle at 0.3 ml every day or night for as long as your protocol lasts (can range from 6 months to years)

Peptide Vials (IGF-1 LR3, 1 mg each): 8 weeks 3 vials (~2.24 mg total needed) 12 weeks 4 vials (~3.64 mg total needed) 16 weeks 6 vials (~5.04 mg total needed) Insulin Syringes (U-100, 0.5 mL or 1 mL): Per week: 7 syringes (1/day) 8 weeks: 56 syringes 12 weeks: 84 syringes 16 weeks: 112 syringes Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution

It works by mimicking the action of ghrelin and binding to the growth hormone secretagogue receptor (GHSR) in the brain, which triggers the pituitary gland to release GH

Modified GRF 1-29 is commonly described as a synthetic analog derived from the first 29 amino acids of the endogenous Growth Hormone Releasing Hormone (GHRH)

The dual-pathway approach engages both the GHRH axis (upstream stimulation of GH synthesis and release) and the ghrelin axis (amplification of GH pulse amplitude) simultaneously, which published preclinical data suggests produces greater GH elevation than either compound alone