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Description

LSECs-derived EVs significantly suppressed proliferation of activated HSCs

BMJ Open Gastroenterol 6, e000315

Research tools for extrapolating the disposition and pharmacokinetics of nanomaterials from preclinical animals to humans

I53-50B.4PT1 was eluted using a 30500 mM imidazole linear gradient in 50 mM Tris pH 8, 500 mM NaCl and 0.75% CHAPS

Through use of the methods of the invention, one can find mutations in B7-1 and B7-2 that only influence binding to one ligand but not to the other, or that improve activity through one ligand while decreasing the activity through the other by stochastic (e.g