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To fill these knowledge gaps, we examined 469 circulating metabolites in a pooled study of 23,634 initially T2D-free and racially/ethnically diverse people from ten prospective cohorts, to identify metabolites associated with incident T2D over up to 26 years of follow-up

In patients with acute heart failure, TMAO was found to be associated with in-hospital mortality and poor prognosis at 1 year

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Use of antipsychotic medication and/or concomitant use of mood stabilizers was permitted

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