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Morronside or vehicle (sterile PBS) was injected into the depilated dorsal skin of C57BL/6 mice in depilation-induced telogen and anagen VI phases (post-depilation day [p.d.] 0 and 12, respectively) 25,30

Since red blood cells are being produced at a slower rate, the old blood cells hang around and grow, leading to a condition known as macrocytic anemia (low blood cell count, but large blood cells)

Additionally, it is important to note that the nature of animal models including closely related strains of species and well-housed environments affect the microbiome in ways not reflective of real-world scenarios

Availabel at Accessed 01/17/2023

Start: Begin at 1.0 mg per injection to gauge tolerability

2a and 18b