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While adverse effects are rare, users should remain aware of potential issues and understand the limitations of current research

Therefore, the clearance of senescent cells through apoptosis is one of the proposed mechanisms to reduce the burden imposed by the presence of senescent cells and in consequence, prevent age-related diseases and ultimately revert aging 3

Protocol Initiation: Treatment begins with conservative dosing that is gradually optimized based on symptom response and lab results

When NAD+ levels are adequate, SIRT1 activity increases, promoting DNA repair, reducing inflammation, and enhancing stress resistance

Researchers need stronger controls, clear endpoints, and proper documentation

Fjell, C.D., Hiss, J.A., Hancock, R.E., and Schneider, G., Nat