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Research increasingly indicates that plant-derived active ingredients support the differentiation and functional capabilities of various cell types, thereby promoting wound healing (Kisseih et al., 2015)

doi: 10.7554/eLife.16246 81 MooreAMCoolenLMLehmanMN

Ravandi F, Cortes J, Faderl S, Garcia-Manero G, O'Brien S, Borthakur G, Pierce S, Brandt M, Lang M, Zhang W, Luthra R, Jones D, Levis M, Konopleva M, Andreeff M , Kantarjian H

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Evensen L, Micklem DR, Blois A, Berge SV, Aarsaether N, Littlewood-Evans A, Wood J, Lorens JB: Mural cell associated VEGF is required for organotypic vessel formation

To ensure translatability, preclinical studies should adopt standardized assays to balance efficacy and safety