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Clinical trial results showed modest and variable weight loss outcomes

Although serious GI tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptoms including epigastric pain, dyspepsia, melena, and hematemesis

For example, individuals with NAFLD exhibit increased intestinal permeability and prevalence of small intestine bacterial overgrowth, and these factors are associated with the severity of hepatic steatosis 19

Given the scoping nature of the review and the heterogeneity of available evidence, study selection focused on identifying representative and clinically informative literature rather than exhaustive quantitative inclusion