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Except for the beneficial effects in the model animals fed normal diets, LA treatment with the same dose significantly attenuated hepatic TG accumulation (via increasing ACC and decreasing FAS) in gene-mutant obesity animals fed an HFD (40% energy from fat) and high-cholesterol diet [88]

183 Notably, a scRNA-seq and TCR-seq study revealed that nearly all TAA-specific Tregs exhibited a Th1-like phenotype within 2 weeks of entering the TME, characterized by downregulation of Foxp3 and marked upregulation of T-bet and IFN-

Aluminum toxicity is dominant in acid soils, and so plants growing in acid soils have to overcome both Al toxicity and N limitation

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Melatonin has anti-aging properties and is extensively reported to combat age-related disorders on both experimental and clinical levels