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Research indicates that M2 macrophage-derived growth differentiation factor 15 confers ferroptosis resistance in the tumor microenvironment, identifying a key drug resistance mechanism (167)

Overall, the lack of long-term improvement in offspring metabolic outcomes suggests that interventions limited to pregnancy may be insufficient to counteract the epigenetic and metabolic consequences of maternal obesity

however, between 10% and 20% on average vary over time

However, this led to a misconception for future research, whereby people believed that ferroptosis must be accompanied by the disturbance of iron metabolism or even iron overload

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In the analyzed samples the average content of the analytes of interest amounted to 185.2 42.6 nmol/mL for Cys, 7.2 4.4 nmol/mL for Hcy, 5.4 3.5 nmol/mL for GSH and 0.92 0.7 nmol/mL for N-Hcy-Lys