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Patients were treated orally with Ershiwuwei Shanhu pills in combination with oral levetiracetam tablets or carbamazepine, and the results showed that the therapeutic effect was higher than that of conventional Western medical treatment, reducing the levels of serum IL-2, TNF-, sICAM-1, IL-6, and CRP

However, progress in the domain of market approval has been limited (Bowles and Setton, 2017) (Table 2) owing to the focus on mechanical restoration rather than biological integration or interaction with local cells