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Several drugs, including colchicine, have been reported to reduce the absorption of methylcobalamin, vitamin B12

Identification of vitamin B12 as a modulator of LRRK2 activity constitutes a huge step forward because it is a neuroprotective vitamin in animal models and has a mechanism unlike that of currently existing inhibitors, Iban Ubarretxena, director of the Biofisika Institute and co-author of the study, said in a press release

Translation to oral administration or to human physiology is unknown

Pernicious Anemia: Parenteral vitamin B 12is the recommended treatment and will be required for the remainder of the patient's life

Primary Handling Editor: Sonia Muliyil, in collaboration with the Nature Medicine team