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Actin Sequestration and Cytoskeletal Regulation The principal mechanism of TB-500 involves binding to the N-terminus of G-actin monomers through the LKKTET hexapeptide motif, forming a 1:1 non-covalent complex that sequesters G-actin from the polymerization-competent pool

Storage requirements Lyophilized (powder) 20C up to 24 months Reconstituted 28C up to 21 days Literature Peer-reviewed research for laboratory background Annals of the New York Academy of Sciences 1997 PMID 9415996 Safer D et al

P., and Kessler, M.: Climatologies at high resolution for the earth's land surface areas, Scientific Data, 4, 120, 2017

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