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doi: 10.1155/2023/1168262 3 Association of Official Analytical Chemists (2005)

In two previous clinical trials, the combination use of vitamin B12 (500 g/day) and folic acid (5 mg/day) for about eight weeks led to a significant improvement in FBG levels and HOMA-IR 41,42

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Indeed, on one hand, CD36 promotes ferroptosis in key anti-tumor immunity cells, CD8 + T lymphocytes, by increasing their uptake of polyunsaturated fatty acids (PUFAs), thereby altering their cytokine production and anti-tumor activity, thus promoting tumor progression [31]