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Modulation of gut microbiota metabolism in obesity-related type 2 diabetes reduces osteomyelitis severity

In contrast, indicator systems that specifically sense particular redox couples allow real-time observation of redox changes (Gutscher et al., 2013)

Mechanism three: glutathione depletion and the oxidative stress spiral Peroxynitrite produced by mechanism one must be neutralized by glutathione (GSH)

Typically, cytoplasmic and nuclear NAD(H) pools are more sensitive to changes in redox stress than the mitochondrial NAD(H) pool, which is stably maintained and required for cell survival under redox insults (108, 120)