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This is a potentially catastophic scenario, because methyl groups are essential for other methylation reactions at other critical junctions

BarbeFDuran-CantollaJSanchez-de-la-TorreMMartinez-AlonsoMCarmonaCBarceloAet al

Schmitt JA, Ramaekers JG, Kruizinga MJ, van Boxtel MP, Vuurman EF, Riedel WJ

The clinical presentation of AZP has significant overlap with other causes of acute gastrointestinal illnesses, including diarrhetic shellfish poisoning (DSP), viral gastroenteritis (e.g., norovirus), and bacterial gastroenteritis (e.g., Vibrio , Salmonella , Escherichia coli , Shigella )

Always apply HA first to buffer and prep the skin

The Aib (2aminoisobutyric acid) residue at the Nterminus improves resistance to enzymatic degradation, while modified amino acids such as D2naphthylalanine and Dphenylalanine enhance stability during laboratory handling