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Description

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

The main mechanism of action is based on the combination of the anorectic effect of GLP-1, the lipolytic and thermogenic characteristics of glucagon, and the action of GIP on -cell function and glycemic control

Therefore, supporting DAO function becomes critical for reducing peptide reactivity

Akkermansia muciniphila is one such beneficial bacterial species known to be less abundant in obese and diabetic individuals and has been implicated in the regulation of intestinal barrier integrity 113